ProSci

CD24 Antibody [30-F1]

Product Code:
 
PSI-98-985
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
IgG2c
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
[30-F1]
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Immunoprecipitation (IP)
Shipping:
 
blue ice
Storage:
 
Store vial at -20˚C
1 / 1
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PSI-98-985-0.5mg0.5mg£673.00
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Further Information

Additional Names:
Heat stable antigen, HSA
Application Note:
CD24 Antibody [30-F1] for use in flow cytometry assays.
Background:
CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory molecule. The CD24 molecule, also known as HSA, is composed mostly of carbohydrate with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property suggesting that the molecule is capable of promoting homotypic aggregation, binding, and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with an anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24 as a ligand for P-selectin, a calcium-dependent lectin.
Buffer:
Supplied in PBS
Concentration:
0.5 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse thymus or spleen
NCBI Gene ID #:
12484
NCBI Official Name:
CD24a antigen
NCBI Official Symbol:
Cd24a
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
P24807
Research Area:
Immunology
SPECIFICITY:
CD24
Swissprot #:
P24807
User NOte:
Optimal dilutions for each application to be determined by the researcher.