Further Information
KCND3, KV4.3, SCA19, SCA22, KCND3L, KCND3S, KSHIVB
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 502-636 of human KCND3 (NP_751948.1).
3752
potassium voltage-gated channel, Shal-related subfamily, member 3
KCND3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 73kDa
Affinity purification
Neuroscience
Q9UK17
Optimal dilutions for each application to be determined by the researcher.