ProSci

SLC1A5 Recombinant Protein

Product Code:
 
PSI-11-460
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Host Type:
 
E.coli
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Shipping:
 
blue ice or RT
Storage:
 
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
 

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PSI-11-460-0.1mg0.1mg£729.00
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Further Information

Additional Names:
ASCT2,M7V1,RDR,RDRC,ATB(0),AAAT,ASCT2M7VS1,M7V1ATBO,R16,RD114,RDRCFLJ31068
Application Note:
This protein carries a polyhistidine tag at the N-terminus, followed by a TrxA tag. The protein has a calculated MW of 22.5 kDa. The protein migrates as 24 KDa under reducing (R) condition (SDS-PAGE).
Background:
Sodium-dependent amino acids transporter(SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).
Background References:
  • Kekuda R., et?al. 1996, J Biol Chem., 271(31), 18657-61.
  • Blond JL., et?al. 2000, J Virol., 74(7), 3321-9.
  • Sugimoto J., et?al. 2017,Sci Rep., 3,1462.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag & TrxA Tag
NCBI Gene ID #:
6510
NCBI Official Name:
solute carrier family 1 member 5
NCBI Official Symbol:
SLC1A5
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
22.5 kDa
Protein Accession #:
NP_005619.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q15758

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