Further Information
Alternate Names/Synonyms:
8-Methyl-N-vanillyl-trans-6-nonenamide; N-[(4-hydroxy-3-methoxyphenyl)methyl]-6E-8-methyl-nonenamide; NSC 56353
White crystalline solid.
404-86-4
6.1
32160000
solid
GHS06, GHS08
Keep cool and dry. Protect from light and moisture.
H301, H315, H317, H319, H334, H335
InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
YKPUWZUDDOIDPM-SOFGYWHQSA-N
Chemical. CAS: 404-86-4. Formula: C18H27NO3. MW: 305.41. Synthetic. Primary active component of the heat and pain-eliciting lipid-soluble fraction of Capsicum pepper. Acts as an agonist at the vanilloid receptor (VR1; TRPV1) receptor, a ligand-gated non-selective cation channel. Capsaicin elicits a sensation of burning pain by activation of TRPV1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. It has been shown to have antinociceptive, anti-inflammatory, anti-obesity, neuroprotective and anticancer effects.
MFCD00017259
C18H27NO3
305.41
Vial
III
P261, P280, P301+P310, P305+P351+P338, P342+P311
Primary active component of the heat and pain-eliciting lipid-soluble fraction of Capsicum pepper. Acts as an agonist at the vanilloid receptor (VR1; TRPV1) receptor, a ligand-gated non-selective cation channel. Capsaicin elicits a sensation of burning pain by activation of TRPV1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. It has been shown to have antinociceptive, anti-inflammatory, anti-obesity, neuroprotective and anticancer effects.
>95% (HPLC)
Danger
COC1=C(O)C=CC(CNC(=O)CCCCC=CC(C)C)=C1
Soluble in ethanol, benzene, ether or chloroform.
Isolated from Capsicum annuum.
Excepted Quantity
UN 2811
Biochemical Reagents
12352200
Stable for at least 2 years after receipt when stored at +4°C.