Chemodex

1-Cyano-4-dimethylaminopyridinium tetrafluoroborate

Product Code:
 
CDX-C0235
Product Group:
 
Other Biochemicals
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
AMBIENT
Storage:
 
Short Term: +4°C, Long Term: -20°C
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Chemical Structure
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Chemical Structure

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CDX-C0235-M100100 mg£84.00
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CDX-C0235-M500500 mg£230.00
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Further Information

Alternate Names/Synonyms:
CDAP
Appearance:
White to yellow powder.
CAS:
59016-56-7
Class:
8
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS05,GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H314, H335
InChi:
InChI=1S/C8H10N3.BF3.FH/c1-10(2)8-3-5-11(7-9)6-4-8;2-1(3)4;/h3-6H,1-2H3;;1H/q+1;;/p-1
InChiKey:
ONCRRSYBEJHQMM-UHFFFAOYSA-M
Long Description:
Chemical. CAS: 59016-56-7. Formula: C8H10N3 . BF4. MW: 235. 1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate (CDAP) is an organic highly effective water soluble cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity. The activation and further carbohydrate modification are produced under mild conditions in an aqueous solvent, an enzyme friendly environment. CDAP can be used with alkaline-sensitive polysaccharides and proteins.
MDL:
MFCD00011998
Molecular Formula:
C8H10N3 . BF4
Molecular Weight:
235
Package Type:
Vial
PG:
II
Precautions:
P260, P271, P280, P301 + P330 + P331, P303 + P361 + P353, P305 + P351 + P338
Product Description:
1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate (CDAP) is an organic highly effective water soluble cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity. The activation and further carbohydrate modification are produced under mild conditions in an aqueous solvent, an enzyme friendly environment. CDAP can be used with alkaline-sensitive polysaccharides and proteins.
Purity:
>97% (NMR)
Signal word:
Danger
SMILES:
CN(C)C1=CC=[N+](C#N)C=C1.FB(F)F.[F]
Solubility Chemicals:
Soluble in acetonitrile or water.
Source / Host:
Synthetic.
Transportation:
Excepted Quantity
UN Nummer:
UN3263
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) J. Kohn & M. Wilchek; FEBS Lett. 154, 209 (1983) | (2) A. Lees, et al.; Vaccine 14, 190 (1996) | (3) S. Bystricky, et al.; Glycoconj. J. 17, 677 (2000) | (4) F. Battaglini & D. Pallarola; Meth. Prot. Meth. Mol. Biol. 739, 161 (2011) | (5) A. Lees, et al.; Vaccines 8, 777 (2020)