NSJ Bioreagents

ACVR1 Antibody / ALK2

Product Code:
 
NSJ-F54223
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Aliquot the ALK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Western blot testing of 1) human A549, 2) human HepG2 and 3) rat testis lysate with ALK2 antibody at 1:1000. Predicted molecular weight ~57 kDa.
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Western blot testing of 1) human A549, 2) human HepG2 and 3) rat testis lysate with ALK2 antibody at 1:1000. Predicted molecular weight ~57 kDa.

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CodeSizePrice
NSJ-F54223-0.08ML0.08ml£260.00
Quantity:
NSJ-F54223-0.4ML0.4ml£502.00
Quantity:
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This product comes from: United States.
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Further Information

Application Details :
Western blot: 1:500-1:1000
Application Note:
Titration of the ALK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 6-34 from the human protein was used as the immunogen for this ALK2 antibody.
Limitation:
This ALK2 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Rat
Uniprot #:
Q04771