TargetMol

AMG2850

Product Code:
 
TAR-T10300
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10300-1mg1mg£177.00
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TAR-T10300-5mg5mg£334.00
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Quantity:
TAR-T10300-1mL1 mL * 10 mM (in DMSO)£362.00
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TAR-T10300-10mg10mg£523.00
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TAR-T10300-25mg25mg£786.00
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TAR-T10300-50mg50mg£1,058.00
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Quantity:
TAR-T10300-100mg100mg£1,412.00
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This product comes from: United States.
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Further Information

Bioactivity:
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).
CAS:
1470018-52-0
Formula:
C19H17F6N3O
Molecular Weight:
417.355
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
C[C@H](NC(=O)N1CCc2cccnc2[C@H]1c1ccc(cc1)C(F)(F)F)C(F)(F)F
Target:
TRP/TRPV Channel

References

1. Lehto SG, et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. Naunyn Schmiedebergs Arch Pharmacol. 2015 Apr;388(4):465-76.