TargetMol

Autogramin-1

Product Code:
 
TAR-T10413
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10413-1mg1mg£257.00
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TAR-T10413-5mg5mg£542.00
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TAR-T10413-1mL1 mL * 10 mM (in DMSO)£619.00
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TAR-T10413-10mg10mg£744.00
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TAR-T10413-25mg25mg£1,099.00
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TAR-T10413-50mg50mg£1,452.00
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TAR-T10413-100mg100mg£1,934.00
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TAR-T10413-500mg500mg£3,805.00
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This product comes from: United States.
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Further Information

Bioactivity:
Autogramin-1 potently inhibits starvation-induced autophagy with IC50 of 0.17 μM. Autogramin-1 also inhibits Rapamycin (mTORC1)-induced autophagy with IC50 of 0.44 μM.
CAS:
2375541-73-2
Formula:
C23H27N5O5S
Molecular Weight:
485.56
Pathway:
PI3K/Akt/mTOR signaling; Autophagy
Purity:
0.98
SMILES:
CCCn1c(=O)[nH]c2cc(ccc2c1=O)C(=O)Nc1nc2CCN(Cc2s1)C(=O)OC(C)(C)C
Target:
mTOR; Autophagy

References

1. Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.