TargetMol

BAY-985

Product Code:
 
TAR-T10477
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10477-1mg1mg£211.00
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TAR-T10477-5mg5mg£369.00
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TAR-T10477-1mL1 mL * 10 mM (in DMSO)£434.00
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TAR-T10477-10mg10mg£550.00
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TAR-T10477-25mg25mg£836.00
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TAR-T10477-50mg50mg£1,107.00
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Quantity:
TAR-T10477-100mg100mg£1,460.00
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This product comes from: United States.
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Further Information

Bioactivity:
BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.
CAS:
2409479-29-2
Formula:
C27H30F3N9O
Molecular Weight:
553.594
Pathway:
NF-κb
Purity:
0.993
SMILES:
C[C@@H](N1CCN(CC1)C(=O)CC(F)(F)F)c1ccnc(Nc2nc3ccc(cc3[nH]2)-c2cc(ncn2)N(C)C)c1
Target:
IκB/IKK

References

1. Lefranc J, et al. Discovery of BAY-985, a Highly Selective TBK1/IKK? Inhibitor. J Med Chem. 2020 Jan 10.