TargetMol

BI-2852

Product Code:
 
TAR-T10533
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10533-1mg1mg£165.00
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Quantity:
TAR-T10533-5mg5mg£304.00
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TAR-T10533-10mg10mg£417.00
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TAR-T10533-25mg25mg£645.00
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TAR-T10533-50mg50mg£863.00
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Quantity:
TAR-T10533-100mg100mg£1,163.00
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This product comes from: United States.
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Further Information

Bioactivity:
BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) with nanomolar affinity. BI-2852 is leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
CAS:
2375482-51-0
Formula:
C31H28N6O2
Molecular Weight:
516.605
Pathway:
GPCR/G Protein; MAPK
Purity:
0.98
SMILES:
Cn1cnc(Cn2ccc3ccc(CNCc4[nH]c5ccccc5c4[C@H]4NC(=O)c5ccc(O)cc45)cc23)c1
Target:
Ras

References

1. Kessler D, et al. Drugging an undruggable pocket on KRAS. Proc Natl Acad Sci U S A. 2019 Aug 6; 116(32):15823-15829.