TargetMol

BVT948

Product Code:
 
TAR-T14841
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14841-1mg1mg£103.00
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Quantity:
TAR-T14841-1mL1 mL * 10 mM (in DMSO)£148.00
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Quantity:
TAR-T14841-5mg5mg£148.00
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TAR-T14841-10mg10mg£185.00
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TAR-T14841-25mg25mg£262.00
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Quantity:
TAR-T14841-50mg50mg£354.00
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Quantity:
TAR-T14841-100mg100mg£493.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor.It can also inhibit lysine methyltransferase SETD8 (KMT5A) and several cytochrome P450 (P450) isoforms.
CAS:
39674-97-0
Formula:
C14H11NO3
Molecular Weight:
241.246
Pathway:
Chromatin/Epigenetic; Metabolism
Purity:
0.987
SMILES:
CC1(C)C(=O)N=C2C1=C(O)C(=O)c1ccccc21
Target:
Phosphatase; P45; Histone Methyltransferase

References

1. Liljebris C, et al. Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione. J Pharmacol Exp Ther. 2004 May;309(2):711-9. 2. Blum G, et al. Small-molecule inhibitors of SETD8 with cellular activity. ACS Chem Biol. 2014 Nov 21;9(11):2471-8. 3. Hwang BM, et al. Protein tyrosine phosphatase controls breast cancer invasion through the expression of matrix metalloproteinase-9. BMB Rep. 2013 Nov;46(11):533-8.