TargetMol

Elexacaftor

Product Code:
 
TAR-T14935
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14935-1mg1mg£142.00
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TAR-T14935-5mg5mg£322.00
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TAR-T14935-1mL1 mL * 10 mM (in DMSO)£402.00
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TAR-T14935-10mg10mg£466.00
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TAR-T14935-25mg25mg£723.00
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TAR-T14935-50mg50mg£978.00
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Quantity:
TAR-T14935-100mg100mg£1,291.00
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This product comes from: United States.
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Further Information

Bioactivity:
Elexacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR) and it also facilitates the processing and trafficking of CFTR to increase the amount of CFTR at the cell surface.
CAS:
2216712-66-0
Formula:
C26H34F3N7O4S
Molecular Weight:
597.66
Pathway:
Autophagy; Membrane transporter/Ion channel
Purity:
0.9887
SMILES:
C[C@@H]1CN(c2nc(ccc2C(=O)NS(=O)(=O)c2cn(C)nc2C)-n2ccc(OCC(C)(C)C(F)(F)F)n2)C(C)(C)C1
Target:
CFTR; Autophagy

References

1. Alexander Russell Abela, et al. MODULATOR OF THE CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR , PHARMACEUTICAL COMPOSITIONS , METHODS OF TREATMENT , AND PROCESS FOR MAKING THE MODULATOR. US 20180162839 A1. 2. Keating D, et al. VX-445-Tezacaftor-VX-770 in Patients with Cystic Fibrosis and One or Two Phe508del Alleles. N Engl J Med. 2018 Oct 25;379(17):1612-1620.