TargetMol

DPA-714

Product Code:
 
TAR-T15162
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15162-1mg1mg£144.00
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TAR-T15162-5mg5mg£254.00
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TAR-T15162-1mL1 mL * 10 mM (in DMSO)£274.00
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TAR-T15162-10mg10mg£369.00
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TAR-T15162-25mg25mg£576.00
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TAR-T15162-50mg50mg£790.00
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TAR-T15162-100mg100mg£1,050.00
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Further Information

Bioactivity:
DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM). It is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. [18F]DPA-714 successfully assesses for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model.
CAS:
958233-07-3
Formula:
C22H27FN4O2
Molecular Weight:
398.482
Purity:
0.9985
SMILES:
CCN(CC)C(=O)Cc1c(nn2c(C)cc(C)nc12)-c1ccc(OCCF)cc1

References

1. James ML, et al. DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization. J Nucl Med. 2008 May;49(5):814-22. 2. Harhausen D, et al. Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke. PLoS One. 2013 Aug 2;8(8):e69529.