TargetMol

NIK SMI1

Product Code:
 
TAR-T16290
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16290-1mg1mg£201.00
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TAR-T16290-5mg5mg£402.00
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TAR-T16290-1mL1 mL * 10 mM (in DMSO)£436.00
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TAR-T16290-10mg10mg£567.00
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TAR-T16290-25mg25mg£862.00
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TAR-T16290-50mg50mg£1,139.00
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Quantity:
TAR-T16290-100mg100mg£1,508.00
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This product comes from: United States.
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Further Information

Bioactivity:
NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23?0.17 nM).
CAS:
1660114-31-7
Formula:
C20H19N3O4
Molecular Weight:
365.389
Pathway:
NF-κb
Purity:
0.9999
SMILES:
COc1cc(nc(c1)-c1cccc(c1)C#C[C@]1(O)CCN(C)C1=O)C(N)=O
Target:
NF-κB

References

1. Blaquiere N, et al. Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-?B Inducing Kinase. J Med Chem. 2018 Aug 9;61(15):6801-6813.