TargetMol

NSC781406

Product Code:
 
TAR-T16355
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16355-1mg1mg£108.00
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TAR-T16355-5mg5mg£148.00
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Quantity:
TAR-T16355-1mL1 mL * 10 mM (in DMSO)£179.00
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TAR-T16355-10mg10mg£201.00
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TAR-T16355-25mg25mg£309.00
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TAR-T16355-50mg50mg£464.00
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Quantity:
TAR-T16355-100mg100mg£645.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
CAS:
1676893-24-5
Formula:
C29H27F2N5O5S2
Molecular Weight:
627.68
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9908
SMILES:
COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nccc(C#CCN3CCN(CC3)S(C)(=O)=O)c2c1
Target:
PI3K; mTOR

References

1. Chen Y, et al. Discovery of benzenesulfonamide derivatives as potent PI3K/mTOR dual inhibitors with in vivo efficacies against hepatocellular carcinoma. Bioorg Med Chem. 2016 Mar 1;24(5):957-66.