TargetMol

MDL-29951

Product Code:
 
TAR-T1897
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1897-1mg1mg£128.00
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TAR-T1897-2mg2mg£148.00
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TAR-T1897-5mg5mg£213.00
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TAR-T1897-1mL1 mL * 10 mM (in DMSO)£217.00
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TAR-T1897-10mg10mg£325.00
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TAR-T1897-25mg25mg£531.00
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TAR-T1897-50mg50mg£732.00
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TAR-T1897-100mg100mg£978.00
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Further Information

Bioactivity:
MDL-29951 is a novel glycine antagonist of NMDA receptor activation.
CAS:
130798-51-5
Formula:
C12H9Cl2NO4
Molecular Weight:
302.11
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9949
SMILES:
OC(=O)CCc1c([nH]c2cc(Cl)cc(Cl)c12)C(O)=O
Target:
NMDAR; iGluR

References

1. Baron BM, et al. Potent indole- and quinoline-containing N-methyl-D-aspartate antagonists acting at the strychnine-insensitive glycine binding site. J Pharmacol Exp Ther. 1992 Sep;262(3):947-56. 2. Wright SW, et al. 3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2055-8. 3. Harden TK. Enigmatic GPCR finds a stimulating drug. Sci Signal. 2013 Oct 22;6(298):pe34.