TargetMol

(S)-Azelastine hydrochloride

Product Code:
 
TAR-T21109
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T21109-1mg1mg£395.00
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Further Information

Bioactivity:
(S)-Azelastine hydrochloride, an antihistamine, has been shown to down-regulate H1R, M1R and M3R levels. It has also been shown to inhibit proliferation of HNEpC.
CAS:
153408-27-6
Formula:
C22H25Cl2N3O
Molecular Weight:
418.36
Purity:
0.98
SMILES:
Cl.CN1CCC[C@@H](CC1)n1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O

References

1. Karpishchenko SA, Kolesnikova OM. [The effectiveness of the combination of azelastine hydrochloride and mometasone furoate for the intranasal application in the patients presenting with seasonal allergic rhinitis]. Vestn Otorinolaringol. 2017;82(5):44-47. doi: 10.17116/otorino201782544-47. Russian. PubMed PMID: 29072663. 2. Liu SC, Lin CS, Chen SG, Chu YH, Lee FP, Lu HH, Wang HW. Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells. Eur Arch Otorhinolaryngol. 2017 Feb;274(2):845-853. doi: 10.1007/s00405-016-4295-8. Epub 2016 Sep 13. PubMed PMID: 27623823. 3. Aksoy F, Senturk E, Do?an R, Veyseller B, Ozturan O, G?n?ll? N, Yilmaz F. Effects of azelastine nasal spray on nasal and nasopharyngeal microflora. J Laryngol Otol. 2016 Jan;130(1):95-9. doi: 10.1017/S0022215115002959. Epub 2015 Oct 30. PubMed PMID: 26515526.