TargetMol

INCB054329

Product Code:
 
TAR-T22345
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22345-1mg1mg£122.00
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TAR-T22345-5mg5mg£195.00
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TAR-T22345-1mL1 mL * 10 mM (in DMSO)£206.00
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TAR-T22345-10mg10mg£269.00
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TAR-T22345-25mg25mg£470.00
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TAR-T22345-50mg50mg£651.00
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Quantity:
TAR-T22345-100mg100mg£863.00
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Further Information

Bioactivity:
INCB054329, a structurally distinct bromodomain and extraterminal domain (BET) inhibitor, inhibits BRD2-BD1, BRD2-BD2, BRD3-BD1, BRD3-BD2, BRD4-BD1, BRD4-BD2, BRDT-BD1 and BRDT-BD2 with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM respectively.
CAS:
1628607-64-6
Formula:
C19H16N4O3
Molecular Weight:
348.36
Pathway:
Chromatin/Epigenetic
Purity:
0.9803
SMILES:
O=C1N2C3=C(C(=CC=C3N1)C=4C(C)=NOC4C)OC[C@@]2(C5=CC=CC=N5)[H]
Target:
Epigenetic Reader Domain

References

1. Stubbs MC, et al. Clin Cancer Res. 2019, 25(1):300-311. 2. Phillip CC Liu, et al. AACR Cancer Res. 2015, 75(15 Suppl):Abstract nr 3523. 3. Wilson AJ, et al. Gynecol Oncol. 2018, 149(3):575-584.