TargetMol

FR 122047 hydrochloride

Product Code:
 
TAR-T22790
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22790-1mg1mg£106.00
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TAR-T22790-5mg5mg£155.00
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TAR-T22790-10mg10mg£212.00
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TAR-T22790-25mg25mg£359.00
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TAR-T22790-50mg50mg£535.00
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TAR-T22790-100mg100mg£736.00
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Further Information

Bioactivity:
FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 ?M for human recombinant COX-1 and COX-2, respectively.
CAS:
130717-51-0
Formula:
C23H25N3O3S?HCl
Molecular Weight:
459.99
Pathway:
Immunology/Inflammation; Neuroscience
Purity:
0.9963
SMILES:
O=C(C1=NC(C(C=C2)=CC=C2OC)=C(C(C=C3)=CC=C3OC)S1)N4CCN(C)CC4.Cl
Target:
COX

References

1. Restrepo B, Garc?a M, L?pez C, Mart?n ML, San Rom?n L, Mor?n A. The cyclooxygenase and nitric oxide synthesis/pathways mediate the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats. Pharmacology. 2012;90(3-4):169-76. 2. Sandberg M, Jansson L. Effects of cyclooxygenase inhibition on insulin release and pancreatic islet blood flow in rats. Ups J Med Sci. 2014 Nov;119(4):316-23. 3. Restrepo B, Garc?a M, Rodr?guez-Barbero A, Rom?n LS, Martin ML, Mor?n A. Participation of cyclooxygenase pathway in the vasoconstriction induced by 5-HT in the in situ autoperfused kidney of long-term diabetic rats. Eur J Pharmacol. 2011 May 20;659(1):37-44.