TargetMol

CYM 50358 hydrochloride (1314212-39-9 free base)

Product Code:
 
TAR-T25282
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25282-1mg1mg£224.00
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Quantity:
TAR-T25282-2mg2mg£301.00
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TAR-T25282-5mg5mg£426.00
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TAR-T25282-10mg10mg£568.00
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TAR-T25282-25mg25mg£863.00
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Quantity:
TAR-T25282-50mg50mg£1,139.00
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Quantity:
TAR-T25282-100mg100mg£1,508.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CYM50358 HCl is an S1P4 antagonist.
CAS:
1781750-72-8
Formula:
C20H19Cl3N2O2
Molecular Weight:
425.73
Purity:
0.9621
SMILES:
NCC1=CC(C)=C(NC(C2=CC=C(C3=CC(Cl)=CC=C3Cl)O2)=O)C(C)=C1.Cl

References

1. Onuma T, Tanabe K, Kito Y, Tsujimoto M, Uematsu K, Enomoto Y, Matsushima-Nishiwaki R, Doi T, Nagase K, Akamatsu S, Tokuda H, Ogura S, Iwama T, Kozawa O, Iida H. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb Res. 2017 Aug;156:91-100. doi: 10.1016/j.thromres.2017.06.001. Epub 2017 Jun 2. PubMed PMID: 28609704. 2. Cencetti F, Bernacchioni C, Tonelli F, Roberts E, Donati C, Bruni P. TGF?1 evokes myoblast apoptotic response via a novel signaling pathway involving S1P4 transactivation upstream of Rho-kinase-2 activation. FASEB J. 2013 Nov;27(11):4532-46. doi: 10.1096/fj.13-228528. Epub 2013 Aug 2. PubMed PMID: 23913862.