TargetMol

Alpidem

Product Code:
 
TAR-T26600
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T26600-1mg1mg£148.00
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TAR-T26600-5mg5mg£229.00
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TAR-T26600-10mg10mg£340.00
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TAR-T26600-1mL1 mL * 10 mM (in DMSO)£372.00
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TAR-T26600-25mg25mg£524.00
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TAR-T26600-50mg50mg£723.00
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TAR-T26600-100mg100mg£978.00
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TAR-T26600-500mg500mg£1,886.00
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Further Information

Bioactivity:
Alpidem is an anxiolytic drug from the imidazopyridine family. Alpidem does not produce sedative effects at normal doses, and is instead used specifically for the treatment of anxiety. Alpidem has nanomolar binding affinity for both the central benzodiaze
CAS:
82626-01-5
Formula:
C21H23Cl2N3O
Molecular Weight:
404.34
Pathway:
Neuroscience; Membrane transporter/Ion channel
Purity:
1
SMILES:
CCCN(CCC)C(=O)Cc1c(nc2ccc(Cl)cn12)-c1ccc(Cl)cc1
Target:
GABA Receptor

References

1. Divya K Nair, et al. Synthesis of imidazopyridines from the Morita-Baylis-Hillman acetates of nitroalkenes and convenient access to Alpidem and Zolpidem. Org Lett. 2012 Sep 7;14(17):4580-3. 2. Natalia Chernyak, et al. General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem. Angew Chem Int Ed Engl. 2010 Apr 1;49(15):2743-6. 3. Andrea Cappelli, et al. Synthesis and structure-activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem. Bioorg Med Chem. 2008 Mar 15;16(6):3428-37. 4. Giuseppe Trapani, et al. Alpidem analogues containing a GABA or glycine moiety as new anticonvulsant agents. Eur J Pharm Sci. 2003 Mar;18(3-4):231-40.