TargetMol

3-Isomangostin

Product Code:
 
TAR-T2S1635
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2S1635-1mg1mg£196.00
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TAR-T2S1635-5mg5mg£338.00
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TAR-T2S1635-1mL1 mL * 10 mM (in DMSO)£382.00
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TAR-T2S1635-10mg10mg£527.00
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TAR-T2S1635-25mg25mg£791.00
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TAR-T2S1635-50mg50mg£1,018.00
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TAR-T2S1635-100mg100mg£1,380.00
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Further Information

Bioactivity:
3-Isomangostin is an acetylcholinesterase selective inhibitor and a potent human aldose reductase inhibitor with an IC50 of 3.48 uM. 3-Isomangostin has free radical scavenging activity and inhibits MutT homolog 1 (MTH1) with an IC50 of 52 nM. It shows antiplasmodial activity with an IC50 values in the range of 4.71-11.40 uM. 3-Isomangostin can be used to develop anticancer agents as well.
CAS:
19275-46-8
Formula:
C24H26O6
Molecular Weight:
410.46
Pathway:
DNA Damage/DNA Repair
Purity:
0.9976
SMILES:
CC(C)(CC1)Oc(cc2Oc(cc3O)c4c(CC=C(C)C)c3OC)c1c(O)c2C4=O
Target:
MTH1

References

1. In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species. Planta Med. 2014 Jun;80(8-9):676-81. 2. Health and Wellness Product from Mangosteen (Garcinia mangostana L.) Rind: Bioactive Potentials. International Journal of Biotechnology for Wellness Industries, 2015, 3(4):111-20.