TargetMol

3'-Hydroxypterostilbene

Product Code:
 
TAR-T2S2382
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2S2382-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T2S2382-20mg20mg£151.00
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Further Information

Bioactivity:
3'-Hydroxypterostilbene, a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene inhibits the p38MAPK , and PI3K/Akt/mTOR/p70S6K pathways and activates the ERK1/2, JNK1/2 MAPK pathways[1].
CAS:
475231-21-1
Formula:
C16H16O4
Molecular Weight:
272.3
Pathway:
Autophagy; Apoptosis
Purity:
0.9919
SMILES:
COc1cc(OC)cc(C=Cc2ccc(O)c(O)c2)c1
Target:
Apoptosis; Autophagy

References

1. Cheng TC, et al. Potent anti-cancer effect of 3'-hydroxypterostilbene in human colon xenograft tumors. PLoS One. 2014 Nov 12;9(11):e111814.