TargetMol

Leteprinim

Product Code:
 
TAR-T32658L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T32658L-1mg1mg£189.00
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TAR-T32658L-5mg5mg£340.00
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TAR-T32658L-10mg10mg£470.00
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TAR-T32658L-25mg25mg£707.00
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Quantity:
TAR-T32658L-50mg50mg£978.00
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Quantity:
TAR-T32658L-100mg100mg£1,291.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Leteprinim is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from astrocytes.
CAS:
138117-50-7
Formula:
C15H13N5O4
Molecular Weight:
327.3
Purity:
0.98
SMILES:
OC(=O)c1ccc(NC(=O)CCn2cnc3c2nc[nH]c3=O)cc1

References

1. Morrone CD, et al. Effects of Neurotrophic Support and Amyloid-Targeted Combined Therapy on Adult Hippocampal Neurogenesis in a Transgenic Model of Alzheimer's Disease. PLoS One. 2016 Oct 21;11(10):e0165393. 2. Di Iorio P, et al. AIT-082 is neuroprotective against kainate-induced neuronal injury in rats. Exp Neurol. 2001 Jun;169(2):392-9. 3. Rathbone MP, et al. AIT-082 as a potential neuroprotective and regenerative agent in stroke and central nervous system injury. Expert Opin Investig Drugs. 1999 Aug;8(8):1255-62. 4. Johnston TH, Brotchie JM. Drugs in development for Parkinson's disease. Curr Opin Investig Drugs. 2004 Jul;5(7):720-6. Review.