TargetMol

Niraxostat

Product Code:
 
TAR-T33676
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T33676-1mg1mg£195.00
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TAR-T33676-5mg5mg£324.00
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TAR-T33676-1mL1 mL * 10 mM (in DMSO)£348.00
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TAR-T33676-10mg10mg£466.00
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TAR-T33676-25mg25mg£703.00
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TAR-T33676-50mg50mg£970.00
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TAR-T33676-100mg100mg£1,267.00
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This product comes from: United States.
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Further Information

Bioactivity:
Niraxostat is one of the isocytosine derivatives as xanthine oxidase inhibitors.
CAS:
206884-98-2
Formula:
C16H17N3O3
Molecular Weight:
299.33
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC(C)(C)COc1ccc(cc1C#N)-n1cc(cn1)C(O)=O
Target:
Xanthine Oxidase

References

Takao Hashimoto,et al.Y-700, a novel inhibitor of xanthine oxidase, suppresses the development of colon aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine-treated mice Biosci Biotechnol Biochem . 2005 Jan;69(1):209-11 Atsushi Fukunari,et al. Y-700 [1-[3-Cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion J Pharmacol Exp Ther . 2004 Nov;311(2):519-28. doi: 10.1124/jpet.104.070433. Epub 2004 Jun 9. B-Rao C, et al. Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits. Bioorganic & Medicinal Chemistry, 2012, 20(9):2930-2939.