TargetMol

CCG215022

Product Code:
 
TAR-T3498
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3498-1mg1mg£148.00
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TAR-T3498-2mg2mg£185.00
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TAR-T3498-5mg5mg£269.00
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TAR-T3498-1mL1 mL * 10 mM (in DMSO)£289.00
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TAR-T3498-10mg10mg£389.00
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TAR-T3498-25mg25mg£603.00
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TAR-T3498-50mg50mg£830.00
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TAR-T3498-100mg100mg£1,099.00
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TAR-T3498-500mg500mg£2,135.00
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This product comes from: United States.
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Further Information

Bioactivity:
CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15?0.07 μM, 0.38?0.06 μM and 3.9?1 μM for GRK2, 5 and 1, respectively.
CAS:
1813527-81-9
Formula:
C26H22FN7O3
Molecular Weight:
499.506
Pathway:
Tyrosine Kinase/Adaptors; GPCR/G Protein
Purity:
0.98
SMILES:
CC1=C(C(NC(=O)N1)c1ccc(F)c(c1)C(=O)NCc1ccccn1)C(=O)Nc1ccc2[nH]ncc2c1
Target:
GRK; PKA

References

Homan KT, et al. Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally DesignedInhibitor. J Biol Chem. 2015 Aug 21;290(34):20649-59.