TargetMol

N-acetyl Dapsone

Product Code:
 
TAR-T35903
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35903-1mg1mg£238.00
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TAR-T35903-5mg5mg£479.00
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TAR-T35903-10mg10mg£663.00
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TAR-T35903-25mg25mg£978.00
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TAR-T35903-50mg50mg£1,299.00
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TAR-T35903-100mg100mg£1,661.00
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Quantity:
TAR-T35903-500mg500mg£3,420.00
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This product comes from: United States.
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Further Information

Bioactivity:
N-acetyl Dapsone is a metabolite of dapsone, an anti-inflammatory and antibacterial compound that is widely used in the treatment of leprosy, malaria, acne, and various immune disorders. Dapsone is acetylated in the liver to monoacetyldapsone, the major metabolite, and other mono and diacetyl derivatives, and subsequently deacetylated back to diaminodiphenylsulfone (dapsone) until a state of equilibrium is achieved.
CAS:
565-20-8
Formula:
C14H14N2O3S
Molecular Weight:
290.34
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
CC(=O)Nc1ccc(cc1)S(=O)(=O)c1ccc(N)cc1
Target:
Antibacterial|Parasite

References

Lemnge MM, et al. Simultaneous determination of dapsone, monoacetyldapsone and pyrimethamine in whole blood and plasma by high-performance liquid chromatography. J Chromatogr. 1993;613(2):340-346. Carr K, et al. Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: a rapid method for determination of acetylator phenotype. Br J Clin Pharmacol. 1978;6(5):421-427. Jarratt MT, et al. Safety and Pharmacokinetics of Once-Daily Dapsone Gel, 7.5% in Patients With Moderate Acne Vulgaris. J Drugs Dermatol. 2016;15(10):1250-1259.