TargetMol

S-NEPC

Product Code:
 
TAR-T36074
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36074-5mg5mg£153.00
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TAR-T36074-10mg10mg£218.00
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TAR-T36074-25mg25mg£398.00
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This product comes from: United States.
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Further Information

Bioactivity:
Cytochrome P450 metabolites of arachidonic acid, such as 11(12)-EpETrE and 14(15)-EpETrE have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. Soluble epoxide hydrolase (sEH) catalyzes the conversion of EpETrEs to the corresponding DiHETrEs thereby diminishing their activity. Inhibitors of sEH may therefore have clinical utility for treating hypertension and systemic inflammation. S-NEPC is a colorimetric substrate used to measure sEH activity. It also is a substrate for Glutathione S-transferase, microsomal epoxide hydrolase and porcine liver carboxylesterase. Hydrolysis of S-NEPC by sEH yields 4-nitrophenol which can be quantified spectrophotometrically at 405 nm. S-NEPC is adaptable for use in 96-well microwell plate readers.
CAS:
147349-28-8
Formula:
C16H13NO6
Molecular Weight:
315.3
Purity:
0.98
SMILES:
O=C(OC1=CC=C([N+]([O-])=O)C=C1)OC[C@H]2[C@@H](O2)C3=CC=CC=C3