TargetMol

Burnettramic Acid A aglycone

Product Code:
 
TAR-T36337
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T36337-1mg1mg£650.00
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Further Information

Bioactivity:
Burnettramic acid A aglycone is a fungal metabolite and an aglycone form of burnettramic acid A originally isolated fromA. burnettiithat has anticancer activity.1It is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 8.4 and >100 μg/ml, respectively).
CAS:
2396676-46-1
Formula:
C35H61NO7
Molecular Weight:
607.9
Purity:
0.98
SMILES:
OCCCCCCC[C@@H](O)CCC[C@@H](O)C/C=C/CCCCCCC[C@@H](C)C[C@H](C)/C(O)=C1C([C@@]2(C[C@H](CN2C1=O)O)[H])=O

References

Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic acids: Rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettiiOrg. Lett.21(5)1287-1291(2019)