TargetMol

4-CPPC

Product Code:
 
TAR-T38293
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38293-1mg1mg£111.00
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TAR-T38293-5mg5mg£168.00
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TAR-T38293-1mL1 mL * 10 mM (in DMSO)£177.00
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TAR-T38293-10mg10mg£230.00
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TAR-T38293-25mg25mg£436.00
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TAR-T38293-50mg50mg£610.00
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TAR-T38293-100mg100mg£838.00
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TAR-T38293-500mg500mg£1,613.00
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Further Information

Bioactivity:
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM).1It is selective for MIF-2 over MIF-1 (IC50= 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
CAS:
29553-70-6
Formula:
C14H9NO6
Molecular Weight:
287.227
Purity:
0.98
SMILES:
OC(=O)c1cccc(c1)-c1cc(ncc1C(O)=O)C(O)=O

References

Tilstam, P.V., Pantouris, G., Corman, M., et al.A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activityJ. Biol. Chem.294(49)18522-18531(2019)