TargetMol

Lumasiran

Product Code:
 
TAR-T39273
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T39273-1mg1mg£724.00
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TAR-T39273-5mg5mg£1,669.00
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Quantity:
TAR-T39273-10mg10mg£2,665.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase . By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1).
CAS:
1834610-13-7
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Garrelfs SF, et al. Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1. N Engl J Med. 2021;384(13):1216-1226. Scott LJ, et al. Lumasiran: First Approval. Drugs. 2021;81(2):277-282.