TargetMol

Prexasertib

Product Code:
 
TAR-T4310
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T4310-1mg1mg£109.00
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TAR-T4310-2mg2mg£139.00
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TAR-T4310-5mg5mg£173.00
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TAR-T4310-10mg10mg£242.00
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TAR-T4310-25mg25mg£414.00
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TAR-T4310-50mg50mg£571.00
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TAR-T4310-100mg100mg£779.00
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Quantity:
TAR-T4310-500mg500mg£1,484.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Prexasertib is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
CAS:
1234015-52-1
Formula:
C18H19N7O2
Molecular Weight:
365.397
Pathway:
Apoptosis; Cell Cycle/Checkpoint
Purity:
0.9728
SMILES:
COc1cccc(OCCCN)c1-c1cc(Nc2cnc(cn2)C#N)n[nH]1
Target:
Apoptosis; Chk

References

Yin Y, et al. Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer. Am J Cancer Res. 2017 Mar 1;7(3):473-483. King C, et al. LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms. Mol Cancer Ther. 2015 Sep;14(9):2004-13