TargetMol

AZD3229

Product Code:
 
TAR-T5409
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5409-1mg1mg£120.00
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TAR-T5409-5mg5mg£189.00
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TAR-T5409-1mL1 mL * 10 mM (in DMSO)£205.00
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TAR-T5409-10mg10mg£262.00
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TAR-T5409-25mg25mg£418.00
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TAR-T5409-50mg50mg£583.00
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Quantity:
TAR-T5409-100mg100mg£787.00
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This product comes from: United States.
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Further Information

Bioactivity:
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel.
CAS:
2248003-60-1
Formula:
C24H26FN7O3
Molecular Weight:
479.516
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.9946
SMILES:
COCCOc1cc(F)c2c(Nc3ccc(NC(=O)Cn4cc(nn4)C(C)C)cc3)ncnc2c1
Target:
c-Kit

References

Kettle JG, et al. Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy) quinazolin-4-yl]amino} phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors. J Med Chem. 2018 Oct 11;61(19):8797-8810.