TargetMol

CH7057288

Product Code:
 
TAR-T5635
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5635-1mg1mg£111.00
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TAR-T5635-5mg5mg£168.00
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TAR-T5635-1mL1 mL * 10 mM (in DMSO)£193.00
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TAR-T5635-10mg10mg£230.00
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TAR-T5635-25mg25mg£369.00
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TAR-T5635-50mg50mg£517.00
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Quantity:
TAR-T5635-100mg100mg£699.00
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Further Information

Bioactivity:
CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.
CAS:
2095616-82-1
Formula:
C32H31N3O5S
Molecular Weight:
569.68
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
Cc1cc(cc(n1)C#Cc1ccc2c3c(oc2c1)C(C)(C)c1cc(NS(C)(=O)=O)ccc1C3=O)C(=O)NC(C)(C)C
Target:
Trk receptor

References

Hiroshi Tanaka, Hitoshi Sase, Toshiyuki Tsukaguchi,et al. Abstract 4179: Potent and selective TRK inhibitor CH7057288[J].10.1158/1538-7445.AM2017-4179 Published July 2017