TargetMol

Firsocostat

Product Code:
 
TAR-T7184
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7184-1mg1mg£141.00
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TAR-T7184-2mg2mg£174.00
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TAR-T7184-5mg5mg£249.00
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TAR-T7184-1mL1 mL * 10 mM (in DMSO)£295.00
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TAR-T7184-10mg10mg£369.00
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TAR-T7184-25mg25mg£502.00
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TAR-T7184-50mg50mg£625.00
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TAR-T7184-100mg100mg£838.00
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Quantity:
TAR-T7184-500mg500mg£1,589.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ND-630 is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
CAS:
1434635-54-7
Formula:
C28H31N3O8S
Molecular Weight:
569.63
Pathway:
Metabolism
Purity:
0.9901
SMILES:
COc1ccccc1[C@H](Cn1c2sc(c(C)c2c(=O)n(c1=O)C(C)(C)C(O)=O)-c1ncco1)OC1CCOCC1
Target:
Acetyl-CoA Carboxylase

References

Li M, Yang J, Ye C, et al. Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Landscape in Neuronal Cells during JEV Infection. Virologica Sinica. 2021: 1-12. Harriman G , Greenwood J , Bhat S , et al. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats[J]. Proceedings of the National Academy of Sciences, 2016:201520686.