TargetMol

Kushenol E

Product Code:
 
TAR-T8214
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8214-1mg1mg£280.00
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Further Information

Bioactivity:
Kushenol E is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM, Ki: 9.5 μM), has anti-tumor activity.
CAS:
99119-72-9
Formula:
C25H28O6
Molecular Weight:
424.493
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC(C)=CCc1c(O)c(CC=C(C)C)c2O[C@@H](CC(=O)c2c1O)c1ccc(O)cc1O
Target:
IDO; Indoleamine 2,3-Dioxygenase (IDO)

References

Kwon M, et al. Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488.