TargetMol

DMH-25

Product Code:
 
TAR-T8569
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8569-1mg1mg£177.00
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TAR-T8569-2mg2mg£230.00
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TAR-T8569-5mg5mg£310.00
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TAR-T8569-1mL1 mL * 10 mM (in DMSO)£370.00
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TAR-T8569-10mg10mg£434.00
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TAR-T8569-25mg25mg£670.00
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TAR-T8569-50mg50mg£914.00
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TAR-T8569-100mg100mg£1,211.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DMH25 is a novel covalent and potent inhibitor of mTOR and shows in vivo antitumor activity against triple-negative breast cancer cells.
CAS:
1685280-21-0
Formula:
C15H8Br3NO3
Molecular Weight:
489.945
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.9905
SMILES:
[O-][N+](=O)C1=Cc2cc(Br)cc(Br)c2OC1c1ccc(Br)cc1
Target:
mTOR

References

am?lie, fouqu?, Delalande O , Jean M , et al. A Novel Covalent mTOR Inhibitor, DHM25, Shows in Vivo Antitumor Activity against Triple-Negative Breast Cancer Cells[J]. Journal of Medicinal Chemistry, 2015:6559-73.