TargetMol

SR33805

Product Code:
 
TAR-T8674
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8674-1mg1mg£125.00
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TAR-T8674-5mg5mg£189.00
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TAR-T8674-1mL1 mL * 10 mM (in DMSO)£217.00
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TAR-T8674-10mg10mg£269.00
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TAR-T8674-25mg25mg£429.00
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TAR-T8674-50mg50mg£600.00
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Quantity:
TAR-T8674-100mg100mg£824.00
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This product comes from: United States.
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Further Information

Bioactivity:
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)
CAS:
121345-64-0
Formula:
C32H40N2O5S
Molecular Weight:
564.74
Pathway:
Membrane transporter/Ion channel; Metabolism
Purity:
0.9894
SMILES:
COc1ccc(CCN(C)CCCOc2ccc(cc2)S(=O)(=O)c2c(C(C)C)n(C)c3ccccc23)cc1OC
Target:
Calcium Channel

References

Mou YA, et, al. Beneficial effects of SR33805 in failing myocardium. Cardiovasc Res. 2011 Aug 1; 91(3): 412-9. Hainaud P, et, al. The calcium inhibitor SR33805 reduces intimal formation following injury of the porcine carotid artery. Atherosclerosis. 2001 Feb 1; 154(2): 301-8. Romey G, et, al. Effects of two chemically related new Ca2+ channel antagonists, SR33557 (fantofarone) and SR33805, on the L-type cardiac channel. Eur J Pharmacol. 1994 Sep 22; 263(1-2): 101-5.