TargetMol

AS1810722

Product Code:
 
TAR-T9043
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9043-1mg1mg£163.00
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TAR-T9043-5mg5mg£269.00
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TAR-T9043-1mL1 mL * 10 mM (in DMSO)£279.00
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TAR-T9043-10mg10mg£389.00
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TAR-T9043-25mg25mg£603.00
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TAR-T9043-50mg50mg£830.00
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Further Information

Bioactivity:
AS1810722 is an orally active and potent STAT6 inhibitor(IC50 :1.9 nM). AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases research.
CAS:
909561-15-5
Formula:
C25H25F2N7O
Molecular Weight:
477.52
Pathway:
Stem Cells; JAK/STAT signaling; Metabolism
Purity:
0.9913
SMILES:
NC(=O)CN1CCN(CC1)c1ccc(Nc2ncc3ccn(Cc4cc(F)cc(F)c4)c3n2)cc1
Target:
P45; STAT

References

Nagashima S , Hondo T , Nagata H , et al. Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors[J]. Bioorg Med Chem, 2009, 17(19):6926-6936.