TargetMol

Enpatoran

Product Code:
 
TAR-T9570
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9570-1mg1mg£168.00
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TAR-T9570-5mg5mg£269.00
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TAR-T9570-1mL1 mL * 10 mM (in DMSO)£303.00
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TAR-T9570-10mg10mg£369.00
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TAR-T9570-25mg25mg£583.00
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TAR-T9570-50mg50mg£838.00
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TAR-T9570-100mg100mg£1,187.00
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TAR-T9570-200mg200mg£1,661.00
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Further Information

Bioactivity:
Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM). Enpatoran was found to be inactive against TLR3, TLR4, and TLR9 in vitro and in vivo.
CAS:
2101938-42-3
Formula:
C16H15F3N4
Molecular Weight:
320.31
Pathway:
Immunology/Inflammation
Purity:
0.98
SMILES:
N[C@H](C[C@@H](C1)C(F)(F)F)CN1c(c1cccnc11)ccc1C#N
Target:
TLR

References

Jaromir Vlach, et al. Discovery of M5049: A Novel Selective TLR7/8 Inhibitor for Treatment of Autoimmunity. J Pharmacol Exp Ther. 2020 Dec 16;JPET-AR-2020-000275.