TargetMol

Buddlejasaponin IV

Product Code:
 
TAR-TN1458
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN1458-5mg5mg£480.00
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Quantity:
TAR-TN1458-1mL1 mL * 10 mM (in DMSO)£689.00
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Further Information

Bioactivity:
Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-kappaB activation.
CAS:
139523-30-1
Formula:
C48H78O18
Molecular Weight:
943.134
Pathway:
Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Cytoskeletal Signaling; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
C[C@H]1O[C@@H](O[C@H]2CC[C@@]3(C)[C@@H](CC[C@]4(C)[C@@H]3C=C[C@]35OC[C@@]6(CCC(C)(C)C[C@@H]36)[C@@H](O)C[C@@]45C)[C@]2(C)CO)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H]1O
Target:
PARP; Akt; Chk

References

Buddlejasaponin IV induces cell cycle arrest at G2/M phase and apoptosis in immortalized human oral keratinocytes.Phytother Res. 2011 Oct;25(10):1503-10.