TargetMol

4beta-Hydroxywithanolide E

Product Code:
 
TAR-TN3070
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN3070-5mg5mg£609.00
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Quantity:
TAR-TN3070-1mL1 mL * 10 mM (in DMSO)£890.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by modulating splicing factors and histone modifications.4bHWE is a useful natural anti-inflammatory compound to attenuate progression of diabetes and obesity, it decreases inflammatory responses by inhibiting the NF-κB signaling in diabetic mouse adipose tissue, it also can improve impaired glucose tolerance.
CAS:
54334-04-2
Formula:
C28H38O8
Molecular Weight:
502.6
Pathway:
Immunology/Inflammation; DNA Damage/DNA Repair; Cytoskeletal Signaling; NF-κb; Neuroscience; Metabolism; Chromatin/Epigenetic
Purity:
0.98
SMILES:
CC1=C(C)C(=O)OC(C1)[C@](C)(O)[C@]1(O)CC[C@@]2(O)[C@@H]3C[C@H]4O[C@]44[C@@H](O)C=CC(=O)[C@]4(C)[C@H]3CC[C@]12C
Target:
PARP; HSP; NF-κB; COX