TargetMol

N-Caffeoyltryptophan

Product Code:
 
TAR-TN7093
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TN7093-1mg1mg£189.00
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TAR-TN7093-5mg5mg£340.00
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TAR-TN7093-1mL1 mL * 10 mM (in DMSO)£357.00
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TAR-TN7093-10mg10mg£470.00
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TAR-TN7093-25mg25mg£707.00
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TAR-TN7093-50mg50mg£978.00
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Further Information

Bioactivity:
N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).
CAS:
109163-69-1
Formula:
C20H18N2O5
Molecular Weight:
366.373
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.98
SMILES:
OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C=Cc1ccc(O)c(O)c1
Target:
Sirtuin

References

Park JB. Finding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 Inhibitor. PLoS One. 2016 Mar 17;11(3):e0150392.