TargetMol

AGN 193109

Product Code:
 
TAR-TQ0097
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-TQ0097-1mg1mg£120.00
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TAR-TQ0097-2mg2mg£144.00
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TAR-TQ0097-5mg5mg£195.00
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TAR-TQ0097-1mL1 mL * 10 mM (in DMSO)£230.00
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TAR-TQ0097-10mg10mg£269.00
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TAR-TQ0097-25mg25mg£470.00
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TAR-TQ0097-50mg50mg£653.00
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TAR-TQ0097-100mg100mg£863.00
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Further Information

Bioactivity:
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).
CAS:
171746-21-7
Formula:
C28H24O2
Molecular Weight:
392.498
Pathway:
Autophagy; Metabolism
Purity:
0.9989
SMILES:
Cc1ccc(cc1)C1=CCC(C)(C)c2ccc(cc12)C#Cc1ccc(cc1)C(O)=O
Target:
Retinoid Receptor; Autophagy

References

Agarwal C, et al. AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells. J Biol Chem. 1996 May 24;271(21):12209-12. Johnson AT, et al. Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors. J Med Chem. 1995 Nov 24;38(24):4764-7. Standeven AM, et al. Specific antagonist of retinoid toxicity in mice. Toxicol Appl Pharmacol. 1996 May;138(1):169-75.