TargetMol

CWHM-12

Product Code:
 
TAR-TQ0250
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-TQ0250-1mg1mg£98.00
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TAR-TQ0250-2mg2mg£109.00
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TAR-TQ0250-5mg5mg£135.00
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TAR-TQ0250-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-TQ0250-10mg10mg£173.00
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TAR-TQ0250-25mg25mg£258.00
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TAR-TQ0250-50mg50mg£383.00
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TAR-TQ0250-100mg100mg£536.00
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Further Information

Bioactivity:
CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).
CAS:
1564286-55-0
Formula:
C26H32BrN5O6
Molecular Weight:
590.47
Pathway:
Cytoskeletal Signaling
Purity:
0.985
SMILES:
OC1=CC(C(NCC(N[C@@H](CC(O)=O)C2=CC(Br)=CC(C(C)(C)C)=C2)=O)=O)=CC(NC3=NCC(O)CN3)=C1
Target:
Integrin

References

Henderson NC, et al. Targeting of ?v integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med. 2013 Dec;19(12):1617-24.