TargetMol

Ebselen

Product Code:
 
TAR-T0825
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0825-5mg5mg£104.00
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TAR-T0825-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T0825-10mg10mg£117.00
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TAR-T0825-25mg25mg£140.00
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TAR-T0825-50mg50mg£163.00
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TAR-T0825-100mg100mg£209.00
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TAR-T0825-200mg200mg£279.00
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Further Information

Bioactivity:
Ebselen is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS). In addition, this agent inhibits the activity of a variety of enzymes including nitric oxide synthase (NOS), 5-lipoxygenase, cyclooxygenase, protein kinase C (PKC), NADPH oxidase and gastric H+/K+-ATPase. Furthermore, ebselen may be neuroprotective due to its ability to neutralize free radicals upon NMDA receptor activation thus, reducing lipoperoxidation mediated by glutamate-induced excitotoxicity.
CAS:
60940-34-3
Formula:
C13H9NOSe
Molecular Weight:
274.192
Pathway:
Metabolism; Membrane transporter/Ion channel; Neuroscience; Immunology/Inflammation; Proteases/Proteasome; Microbiology/Virology
Purity:
0.9994
SMILES:
O=c1n([se]c2ccccc12)-c1ccccc1
Target:
Phosphatase; Virus Protease; Calcium Channel; COX; HIV Protease

References

1. Schewe T. Gen Pharmacol, 2009, 26 (6): 1153?69.