TargetMol

ATN-161 trifluoroacetate salt

Product Code:
 
TAR-T10397
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10397-1mg1mg£101.00
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TAR-T10397-2mg2mg£114.00
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TAR-T10397-5mg5mg£142.00
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TAR-T10397-10mg10mg£173.00
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TAR-T10397-25mg25mg£261.00
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TAR-T10397-50mg50mg£389.00
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TAR-T10397-100mg100mg£544.00
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Further Information

Bioactivity:
ATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of liver metastases and improves survival in a murine model.
CAS:
904763-27-5
Formula:
C25H36F3N9O10S
Molecular Weight:
711.67
Pathway:
Cytoskeletal Signaling
Purity:
0.9998
SMILES:
OC(=O)C(F)(F)F.CC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(N)=O
Target:
Integrin

References

1. Stoeltzing O, et al. Inhibition of integrin alpha5beta1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice. Int J Cancer. 2003 Apr 20;104(4):496-503. 2. Wang W, et al. The antiangiogenic effects of integrin alpha5beta1 inhibitor (ATN-161) in vitro and in vivo. Invest Ophthalmol Vis Sci. 2011 Sep 14;52(10):7213-20.