TargetMol

Col003

Product Code:
 
TAR-T10860
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10860-2mg2mg£104.00
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TAR-T10860-5mg5mg£124.00
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TAR-T10860-10mg10mg£161.00
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TAR-T10860-25mg25mg£256.00
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TAR-T10860-50mg50mg£367.00
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TAR-T10860-100mg100mg£529.00
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This product comes from: United States.
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Further Information

Bioactivity:
Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investigation of fibrosis.
CAS:
328565-16-8
Formula:
C14H11NO4
Molecular Weight:
257.245
Pathway:
Cytoskeletal Signaling; Metabolism
Purity:
0.9903
SMILES:
Oc1c(C=O)cc(Cc2ccccc2)cc1[N+]([O-])=O
Target:
HSP

References

1. Ito S, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017 Dec 8;292(49):20076-20085.