TargetMol

Miglustat

Product Code:
 
TAR-T12039
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12039-1mg1mg£101.00
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TAR-T12039-5mg5mg£142.00
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TAR-T12039-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T12039-10mg10mg£182.00
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TAR-T12039-25mg25mg£278.00
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TAR-T12039-50mg50mg£414.00
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TAR-T12039-100mg100mg£571.00
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Further Information

Bioactivity:
Miglustat is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).
CAS:
72599-27-0
Formula:
C10H21NO4
Molecular Weight:
219.281
Purity:
0.9975
SMILES:
CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

References

1. Abian, O., et al., Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase. Mol Pharm, 2011. 8(6): p. 2390-7. 2. van Giersbergen, P.L. and J. Dingemanse, Influence of food intake on the pharmacokinetics of miglustat, an inhibitor of glucosylceramide synthase. J Clin Pharmacol, 2007. 47(10): p. 1277-82.