TargetMol

C527

Product Code:
 
TAR-T14852
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14852-5mg5mg£108.00
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Quantity:
TAR-T14852-10mg10mg£135.00
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TAR-T14852-25mg25mg£209.00
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TAR-T14852-50mg50mg£302.00
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Quantity:
TAR-T14852-100mg100mg£458.00
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This product comes from: United States.
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Further Information

Bioactivity:
C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for the USP1/UAF1 complex (IC50=0.88 μM).
CAS:
192718-06-2
Formula:
C17H8FNO3
Molecular Weight:
293.253
Pathway:
DNA Damage/DNA Repair; Ubiquitination; Cell Cycle/Checkpoint
Purity:
0.9764
SMILES:
Fc1ccc(cc1)-c1nc2c(o1)C(=O)c1ccccc1C2=O
Target:
DUB

References

1. Mistry H, et al. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec;12(12):2651-62.